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Meta-analysis reveals reproducible gut microbiome alterations in response to a high-fat diet (in Eng)
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The gap between correct dosing and dosing errors comes down to three calculations most guides gloss over: determining final concentration after reconstitution, converting that concentration to injection volume, and accounting for vial overfill that changes the actual amount of peptide present
While this sounds encouraging, we must recognize this was not a controlled trial there was no placebo group, and the patients (and doctors) knew they were receiving the peptide
Phase 2 trials (Jastreboff et al., NEJM, 2023) have shown it to be highly effective for weight reduction in adults with obesity
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