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ERR target-gene expression (for example, Ppargc1a, Tfam, OXPHOS subunits), oxygen-consumption rate in cells, and, in vivo, indirect calorimetry parameters (energy expenditure, RER), plus mitochondrial DNA and cytochrome-c content in muscle

The legal basis for the study was consent according to General Data Protection Regulation principles

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Estrogen receptors are densely distributed in skin fibroblasts and hair follicles