Neuroendocrinology , 2022 , 112
Rubn Oseguera Gonzlez, 34, better known as El Menchito, is part of a generation of narco juniors learning that the old-school codes of silence and family loyalty that once protected their fathers are increasingly relics of the past
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The peptide activates extracellular signal-regulated kinase 1/2 (ERK1/2) phosphorylation in a dose-dependent manner, leading to nuclear translocation and activation of transcription factors including c-Fos, c-Jun, and early growth response-1 (Egr-1) that drive expression of genes involved in cell growth, migration, and angiogenesis
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