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[1] These are meaningful cosmetic endpoints, and they map logically onto the mechanism: more collagen and glycosaminoglycan synthesis, better-organized remodeling, and reduced oxidative and inflammatory burden should, in principle, translate into firmer, smoother, more resilient skin

Due to disassembly of the complex upon dilution to nanomolar concentrations required for mass photometry, we stabilised it by limited crosslinking using glutaraldehyde prior to dilution to assess potential TRF1 dissociation (Supplementary Fig

The tissue specimens were fixed using 10% neutral buffered formalin for 24 h and embedded in paraffin blocks

Sterile water isn't preserved

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