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The transdermal composition of claim 2 which provides at least one of the following release pattern in an In Vitro study employing dialysis membrane and a phosphate buffer of pH 7.4 i) at least 30 % release in 24 hrs and 70 % release in 72 hrs

It does not interact with estrogen or testosterone pathways and has no known risk of virilization or masculinizing effects, making it an ideal option for female athletes focused on recovery, body composition, or anti-aging

Vascular endothelium injuries are known to precede the development of and to be an essential prerequisite for gross organ injuries

Datwani A, McConnell MJ, Kanold PO, Micheva KD, Busse B, Shamloo M, et al

Nat Rev Neurosci 5 : 173183