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Nicholls SJ, Lincoff AM, Garcia M, et al

Higher levels of the 16-OH metabolite can cause heavy periods, breast tenderness, breast cancer, obesity, hypothyroidism, pesticide toxicity (organochlorines), high omega-6 fatty acids, and inflammatory cytokines

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We then calculated the IC 50 (50% inhibitory concentration) values derived from SWI/SNF-proficient cell lines and SMARCA4-, SMARCB1- and PBRM1-deficient cell lines treated with eprenetapopt (Fig