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For all the aforementioned experiments, the Dual-Luciferase Reporter Assay System (Promega Corporation) was used to measure luciferase activity strictly according to the manufacturers instructions

Chamorro-Garcia A, Gerson J, Flatebo C, Fetter L, Downs AM, Emmons N, Ennis HL, Milosavi N, Yang K, Stojanovic M, Ricci F, Kippin TE, Plaxco KW (2022) Real-time, seconds-resolved measurements of plasma methotrexate in situ in the living body

In chronic gastritis, the irritant causing stomach irritation should be removed

Conversely, lowering the dose may render the treatment ineffective