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By using the method of Peto and colleagues (1992) or one of its variants to derive estimates of total smoking-related mortality from data on lung cancer mortality, it is possible to compare smoking-related deaths across countries and through time and thus to estimate the role of smoking in the divergence in life expectancy trends

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Alternatively, it could also imply that the availability of disposable flavored e-cigarettes has led to a product substitution where individuals that previously used flavored e-cigarette pods with replaceable cartridges now use flavored e-cigarettes with disposable cartridges 35