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Compromised axonal protein transport post-TBI (Lifshitz et al., 2007) and intracellular protein accumulation such as Beta-amyloid precursor protein (-APP) at the point of axonal breakage forms retraction bulbs/swelling (Risdall et al., 2011)

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People with a history of cancer should be particularly wary, as IGF-1 (which increases with CJC-1295) may be involved in the development of certain types of cancer

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