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Theoretical concerns about chronic NNMT inhibition include effects on the metabolism of other quinolinium and methylpyridinium endogenous metabolites and on the broader cellular methylation landscape

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Understanding this is the foundation for understanding why dosing is not a one-size-fits-all figure: the molecule behaves differently from the compounds people often group it with

The reason to show it long-hand rather than just stating the answer is that on the 10 mg vial the draw is tiny, and a reader who understands the chain can catch an error the moment a number looks wrong

That matters because, unlike most peptides, a small molecule can be studied orally as well as by injection it has no peptide bonds for digestive enzymes to cleave