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This trial, while not showing superiority of JTA-004 over placebo in the overall population, provides highly valuable insights into clinical trial design, placebo responses, and the potential need for better patient stratification in osteoarthritis research

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10.1262/jrd.10-198e 90 InoueN.Matsuda-MinehataF.GotoY.SakamakiK.ManabeN

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It is a tripeptide with a gamma peptide linkage between the carboxyl group of the glutamate side chain and the amine group of cysteine, and the carboxyl group of cysteine is attached by normal peptide linkage to a glycine