GGT metabolizes glutathione (GSH), which defends against free radicals from poor diet, alcohol, tobacco, and medications
Experimental investigations have reported interactions with VEGFR2 phosphorylation, focal adhesion kinase (FAK) activation, ERK1/2 signaling, nitric oxide-associated pathways, and extracellular matrix regulatory networks
The recombinant proteins of AsGGT1, AsGGT2, and AsGGT3 exhibited considerable deglutamylation activity toward a putative alliin biosynthetic intermediate, -glutamyl- S -allyl-L-cysteine, whereas these proteins showed very low deglutamylation activity toward another possible alliin biosynthetic intermediate, -glutamyl- S -allyl-L-cysteine sulfoxide
Vitamin C, in the form of L-ascorbic acid, supports collagen production and skin renewal, reducing the appearance of wrinkles, fine lines, and other signs of aging
As such, they have concluded that patients who suffer from severe COVID impact tend to be the ones most deficient in Glutathione
