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Front Endocrinol (Lausanne) 14:1169624 Begum S, Hossain MJ, Kim I, Min HS, Lim YN, Cho HJ et al (2025) Modulating immune responses in alopecia: therapeutic insights and potential targets of antisense oligonucleotides

High SASP-secreting cells are likely to play a much larger role in disease development than more sterile senescent cells

Although insulin deficiency is the primary defect in T1D, in patients with poorly controlled T1D there is also a defect in the ability of target tissues to respond to the administration of insulin

Furthermore, carbonylation of proteins involved in fibrinolysis, for instance plasminogen, cannot be excluded as a contributor to hypofibrinolysis as shown in patients with pulmonary embolism [11]