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Semaglutide patients had: 7.7 lbs (3.5 kg) more weight loss than placebo (with a 1 mg injection dose) 5.7 lbs (2.6 kg) more weight loss than placebo (with a 0.5 mg injection dose) Ozempic injection helped with weight loss and weight loss maintenance when used with diet and exercise in clinical trials, however, it is not FDA-approved for weight loss