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discovered that in prostate cancer (PCa), vitamin C (VC) can induce oxidative stress and apoptosis by inhibiting GS

The gradual decline of the natural supply of glutathione in the body is believed to be a key marker of many outward signs of ageing, adds Heather Wish, Education Manager at Paulas Choice

Although repurposing existing drugs offers a cost-effective and time-efficient alternative for identifying new therapies, their effective concentrationsmeasured as the half-maximal inhibitory concentration (IC50)often exceed the maximum safe plasma levels in humans, creating a major barrier to clinical application

Demircan K, Chillon TS, Bang J, Gladyshev VN, Schomburg L (2024) Selenium, diabetes, and their intricate sex-specific relationship

Next, we conducted confocal laser scanning microscopy (CLSM) and observed the presence of large aggregates with a high intensity of fluorescence signals (Fig