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Since vitamin B12 is derived from animal-based sources, individuals who do not eat meat or animal byproducts can experience deficiencies if they do not use supplemental sources

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Additionally, the ncAA incorporation sites must be selected carefully, as the inappropriate incorporation could impact the antibody stability and binding affinity

Safety and Monitoring : Given the potential risks, especially related to tumor growth due to increased angiogenesis, it is crucial to monitor health metrics and use the minimum effective dose

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