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Adverse events reported in the Phase 3 trials include [5]: Baseline and periodic measurement of serum IGF-1 and fasting glucose are recommended, particularly for off-label applications and in patients with metabolic risk factors [4], [5]

Rarely, allergic reactions can occur, presenting as hives, difficulty breathing, or swelling of the face, lips, tongue, or throat

Once the peptide is mixed with a liquid solution, it becomes highly vulnerable to heat and bacterial growth

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Regulatory and commercial factors rather than safety concerns explain this limitation