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Shuo Hu, [email protected] These authors have contributed equally to this work This article was submitted to Biomaterials, a section of the journal Frontiers in Bioengineering and Biotechnology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Stacking with other peptides targeting different mechanisms (such as GH secretagogues that work through the GHRH axis rather than direct fat-cell signalling) is theoretically additive