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Signal transduction and epigenetic mechanisms in the control of microglia activation during neuroinflammation

Our data are consistent with a number of studies indicating that oxidative stress results in a marked increase in GSSG, a decrease in the GSH/GSSG ratio, and decreased total GSH [21-23]

Given these multiscale findings, spatiotemporal level changes in brain GSH and other antioxidants may indicate that certain brain regions, in particular, metabolically expensive hub regions (e.g., posterior cingulate cortex) (Badhwar et al., 2017, Tomasi et al., 2013), are more vulnerable to aging-related OS (Badhwar et al., 2017, Hahn et al., 2022, Tomasi et al., 2013)

So, when it comes to the best antioxidants for sleep, glutathione is arguably one of the most important

You can also catch him with his amazing family, listening to music (especially U2), watching sports, or relaxing with dog Snowy