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Experts who spoke with BioSpace prior to the approval are hopeful that this small molecule will be a game-changer in terms of both diagnosis of and treatment for MASH

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For example, the upregulation of the Nrf2 pathway by lipoic acid in cultured hepatocytes and in the liver of obese or diabetic rats prevented lipid overload-induced steatosis (35) and cell death (36)

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