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For observational studies (cohort and case-control), the NewcastleOttawa Scale (NOS) (La Torre et al., 2014), was applied

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In vitro , in comparison with control, healthy animals, the assessment of splenic cells (day 21) demonstrated that the 6-methylprednisolone animals had declined reactivity to nitrogen, while the addition of BPC 157 (1 g/g cream) returned cell reactivity to normal values (Mikus et al., 2001

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