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Vitamin B12 (aka cobalamin) is a vitamin that plays an important role in red blood cell production, brain health, and DNA synthesis

In addition, increasing STAT3 from activated JAK/STAT signaling pathway might be involved in the apoptosis of cell through PTEN, which inhibits Akt cascade, resulting in exacerbated hyperglycemia 136 (Fig

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Glutathione membantu menyeimbangkan kadar radikal bebas dalam tubuh, sehingga mengurangi risiko penyakit seperti kanker, diabetes, dan rheumatoid arthritis

HIF-1 is activated due to blockade of its degradation pathway mediated by low oxygen levels, thereby increasing the expression of target genes, including those encoding glycolytic enzymes and glucose transporters, and increasing lactate secretion 67