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Novel druggable mechanism of Parkinsons disease: Potential therapeutics and underlying pathogenesis based on ferroptosis

These synaptogenesis proteins have been more or less associated with synaptic plasticity, but the interplay between them, the profound mechanistic process involved in the regulation of synaptic plasticity by neurexins, and the possible associations with sustained antidepressant effect have not yet been elucidated in detail and need to be further reviewed and explored by researchers

The stability of a protein disulfide bond is determined by its intrinsic stability, K eq , plus the ratio of the concentrations of GSH and GSSG: Only very stable protein disulfide bonds, with large values of K eq , could be populated in the cytosol

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2024;16:S2436