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Here, microbiome-derived short-chain fatty acids (SCFAs) and anti-inflammatory metabolites can suppress NLRP3 activity by inhibiting ROS production and modulating histone acetylation, promoting tissue homeostasis [31]

Angiogenesis helps promote cell generation and healing, which is important in the formation of new blood vessel networks and the wound-healing process

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Subsequent research uncovered that the HGF-MET signaling pathway triggers the PI3K pathway, which in turn triggers Arg-1 expression in a dependent manner, propelling M1 macrophages to adopt an M2-like phenotype [66]

Inflammopharmacology 14 (5-6), 214221