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Tumor-induced glutamine competition promotes glutamate secretion to modulate immune responses Cancer cells strengthen their resistance to tumor-infiltrating lymphocytes (TILs) partly through the metabolites released into the TME, contributing to its hostility

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In senescence-accelerated murine models, TERT activation by Epithalon correlates with increased median and maximal lifespan, reduced incidence of cytogenetic anomalies in bone marrow metaphases, and improved resistance to oxidative and genotoxic stress 2,4

In mammals, WAT is the main site for the storage of triacylglycerol