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doi: 10.3389/fmed.2026.1783433 Received 08 January 2026 Revised 24 February 2026 Accepted 27 February 2026 Published 25 March 2026 Volume 13 - 2026 Edited by Hua Li, Air Force Medical University, China Reviewed by Hazem Mohammed Shaheen, Damanhour University, Egypt Baonian Liu, Shanghai University of Traditional Chinese Medicine, China Updates Copyright 2026 Wang, Zou, Chen, Cui, Huang, Chen, Qi, Nan, Wang and Shang

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18 The treatment protocol for TPE consists of removing and retaining a considerable volume of plasma, approximately 1 to 1.5 plasma volume, 17 and returning the necessary cellular components via a colloid or combination colloid/crystallization solution of either fresh frozen plasma (FFP) or albumin

Gut microbiota impacts bone via Bacteroides vulgatus-valeric acid-related pathways