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This inter-organ crosstalk provides new insights into the maintenance of health homeostasis and the development of systemic dysbiosis under disease conditions

This is particularly important for CRC as rapidly expanding tumors require an enhanced blood supply (2931)

We know enough to be dangerous

TIRZ is simply the short form of Tirzepatide used by researchers it is the same dual-agonist research peptide

Acknowledgements The authors thank L Johnson, L Wilkins, S Bound, S Oliver, J Martin, R Meeny, N Blasch, and F Dabrowski for animal care, S Holloway and J House for veterinary care, L Potenza and C Burstrm for excellent technical assistance, and A Samson for insightful advice