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Together, they enhance pituitary stimulation, offering a valuable model for studying growth hormone regulation, tissue regeneration, metabolism, and endocrine functions

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Moreover, the brain ACh like several other brain neurotransmitters, e.g., DA, 5-HT and GABA, playing a key role in ASD are regulated by different central mechanisms including histamine H3 hetero-receptors (H3Rs), highlighting the attention to brain histaminergic system involvement in the ASD (Sadek and Stark, 2015

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