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We also examined gene expression changes induced by C1-27 in HCT116 cells after 4 and 24 h treatment to observe the early and late response to GSTO1 inhibition, respectively (Supplementary Tables 1417 and 2023)
6,7,8,9,10 Moreover, through NAMPT activation, SIRT1 is involved in the regulation of several stemness signaling factors, such as the tumor suppressor Hippo pathway, 184 c-Myc-mediated OCT4 interaction, 78,185 NICD from the Notch pathway and Gli1 and Gli2 from the Hedgehog pathway
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10.1007/s13277-013-1020-8 138 LeA.LaneA
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