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O is able to either reduce or oxidize transition metals (e.g., iron, copper) ( destroys the Fe-S clusters of proteins, and the reduced iron undergoes additional redox reactions that cause more injuries, as described below ( Hydrogen peroxide As shown in Reaction 2, Fe(II) returns to the oxidized Fe(III) state, in the process catalyzing the production of H 2 O 2

In addition, small intestine and colon length were transiently reduced at the onset of arthritis (Fig

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