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Of note, transcription of cyclin-dependent kinase inhibitor, p21 ( CDNK1A ) was significantly upregulated in response to GSTO1 knockdown while that of the cell cycle regulatory proteins cyclin D1 ( CCND1 ), cyclin E1 ( CCNE1 ), as well as Myc were found downregulated (GEO accession No

Microglia promote remyelination independent of their role in clearing myelin debris

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It was previously reported that type II diabetic patients taking metformin, similar to phenformin, showed a reduced risk of severe COVID-19 compared to non-users 42