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Increased risks of heart attacks: Hormone treatments (e.g., testosterone) increase the risk of heart attack, stroke, and blood clots.Cancer risk: Long-term use of growth hormone or sex hormones may raise the risk of certain cancers (e.g., breast, prostate).Mood changes: Hormone imbalance can lead to mood swings, anxiety, or depression.Illegal use: Some medications, like human growth hormone (HGH), are illegal for anti-ageing use and carry legal risks.Poor regulation of compounded drugs: Compounded drugs are not a standardised product, appear to carry some risk of contamination, possibly present in the wrong dosage, and potentially contain harmful additives.No proven long-term benefit: Many anti-ageing treatments show little or only temporary benefit, and the long-term safety of such treatments is unknown.Misleading marketing: Treatments are often marketed with claims that greatly exceed any support from scientific research.Also read | Struggling with weak nails
doi: 10.1016/j.cell.2016.10.043 80 KhanSWaliullahSGodfreyVKhanMAWRamachandranRACantarelBLet al
It is provided for education and is not a substitute for professional medical advice
Conclusions and perspectives Although prior reviews have laid important groundwork in understanding the transcriptional and epigenetic control of autophagy, most notably the foundational contributions by Fllgrabe et al
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