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Upon receptor engagement in research models, IGF-1 LR3 activates two major downstream signaling cascades: - PI3K/Akt/mTOR pathway associated with cellular survival, protein synthesis, and anabolic signaling processes in experimental models

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[DOI] [PMC free article] [PubMed] [Google Scholar] 110.Kruis W., Fric P., Pokrotnieks J., Lukas M., Fixa B., Kascak M., Kamm M.A., Weismueller J., Beglinger C., Stolte M., et al

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Stanley CA, Lieu YK, Hsu BYL, Burlina AB, Greenberg CR, Hopwood NJ, et al