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599 The interlaminar astrocytes (which populate brains of high primates and are not present in other species 32,33 ) are highly vulnerable to AD pathology: at the advanced stages of the disease interlaminar astrocytes disappear, 600 although how this impacts on the disease pathophysiology remains unknown

For elbow tendinopathy, local injection near the affected area delivers the highest concentrations directly to damaged tissue

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In the UK, B12 replacement is typically administered via intramuscular hydroxocobalamin injections for patients with confirmed deficiency, particularly those with malabsorption or pernicious anaemia, as specified in the BNF and NICE CKS guidance on B12 and folate deficiency anaemia