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26(2): S182 Zhang AQ, Mitchell SC, Ayesh R, et al

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The heavy subunit catalyzes formation of -glutamylcysteine, whereas the light subunit increases affinity for glutamate and decreases the inhibition by glutathione (Seelig et al., 1984

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qRT-PCR experiment was performed using 2X SG Fast qPCR Master Mix (High Rox) (Bio Basic Inc, Markham ON, Canada) in the QuantStudioTM 1 Plus System (Thermo Fisher Scientific, Massachusetts, USA)