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Dosages reported in the research literature: Reported protocols: Loading phase (weeks 1-4): Daily administration at the higher dosages to establish tissue levels

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Overgrowth of bacteria: Some people develop vitamin B 12 deficiency as a result of conditions that slow the movement of food through the intestines (diabetes, scleroderma, strictures, diverticula), allowing intestinal bacteria to multiply and overgrow in the upper part of the small intestine

This includes genes involved in collagen synthesis, antioxidant defense, DNA repair, stem cell function, and inflammation