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Caspases 3 and 7, key mediators of the mitochondrial apoptotic pathway, were significantly activated by (M+D)/2 after 24 hours in IMR-5/75 -Dox and IMR-32, but not in Be(2)-C and SH-SY5Y/MYCN cells

Author contributions SE: Conceptualization, Formal Analysis, Investigation, Methodology, Validation, Visualization, Writing original draft, Writing review & editing

More water means more volume per dose, which means larger injections

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