MMP-responsive particles use peptide sequences cleavable by MMP-2 or MMP-9 to induce size reduction, disassembly or drug release in matrix-rich tumor regions [84], while collagenase or matrix-degrading peptide-loaded platforms aim to lower local collagen or hyaluronan density and reduce interstitial pressure [96]
SECOND OPINION SERIES Natural Treatment for OCD Symptoms: Glutamate, NMDAR, Diet and Biochemical Patterns A natural treatment for OCD symptoms should look beyond serotonin alone and ask whether glutamate overload, NMDA receptor overactivity, undermethylation, copper-zinc imbalance, histamine reactivity, oxidative stress, toxic burden, or mitochondrial strain is driving the intrusive thought loop
Hidrox and chronic cystitis: biochemical evaluation of inflammation, oxidative stress, and pain
Dimova, S., Hoet, P
In breast cancer, TNF- serves multiple functions in disease progression and metastasis