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Maisenbacher HW 3rd, Shroads AL 3rd, Zhong G, Daigle AD, Abdelmalak MM, Samper IS, et al

Upon activation, GPER stimulates intracellular signaling cascades, including the PI3K/AKT and MAPK/ERK cascades, which further augment mitochondrial respiratory chain activity and ATP production [218]

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in comparison, 14% of patients in the NIH DILIN study had persistent laboratory test result abnormalities