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Intramuscular administration of vitamin B12 is often preferred for its rapid improvement in patients with severe deficiency or severe neurological symptoms

The NHS notes that taking up to 2,000 micrograms daily is unlikely to cause harm in most people, though there is generally no benefit to such excessive amounts without confirmed deficiency

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In addition to vitamin B12, experts also recommend adding vitamin B9 or folic acid

Mood changes such as irritability, depression, or anxiety, as well as numbness or tingling in the hands and feet, can also be linked to low B12 levels