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King and Corkery 5 suggested an index of fatal toxicity for drugs of misuse that was calculated as the ratio of the number of deaths associated with a substance to its availability
Ng M, Freeman MK, Robinson M, Fleming TD, Dwyer-Lindgren L, Thomson B, Wollum A, Sanman E, Wulf S, Lopez AD, Murray CJL, Gakidou E: Smoking prevalence and cigarette consumption by age and sex in 187 countries from 1980-2012
Working Group for the Study of Transdermal Nicotine in Patients with Coronary artery disease
However, there is a huge difference in the ingredients found in one cigarette versus one e-liquid bottle