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This is in line with the antigen-specificity of the response promoted by peptide immunotherapy, and resulted in the suppression by the pCons-induced T regs of the proliferation of CD4 + CD25 - T effectors cells and reduced production of proinflammatory cytokines

There was a steady increase in mean sensitivity during the treatment period in each cohort, which was greatest in cohort 3 at 0.15 dB/month (p = 0.008)