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Metal: Weight:66 g Dimensions:Height: 0.6 in (15 mm)Width: 2.76 in (70 mm)Length: 3.15 in (80 mm) Style: Place of Origin: Period: Date of Manufacture:1800 Condition:Minor losses

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Rubinstein ML, Delucchi K, Benowitz NL, Ramo DE

Each step has a strong genetic component (for example, twin-based heritability estimates up to 70% for the transition from regular smoking to ND 3,4 ) and partial overlaps are expected among the sets of sequence variants correlating with the different stages 3 , as evidenced by findings of the GWAS and Sequencing Consortium of Alcohol and Nicotine use (GSCAN) with sample sizes up to 1.2 million individuals 5