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10.3389/fimmu.2023.1163585 Front Immunol

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Animal Model:Naturally aged male C57BL/6 mice (20-24 months old) [1] Dosage:5 mg/kg Administration:Intraperitoneal injection, every other day for three administrations Result:Increased serum testosterone levels

Possible signs include jawline prominence, enlarged hands/feet, coarse facial features, and organ enlargement (rare and associated with long-term abuse)