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These cells appear to contribute to the aging process and age-related diseases through the senescence-associated secretory phenotype (SASP), which fosters a pro-inflammatory environment detrimental to tissue function and integrity

Anti Oxidant Properties: Glutathione stimulates pheomelanin synthesis rather than the darker melanin

Kraft found that the expression of GCH1 triggered the production of potent antioxidant BH4, thus preventing lipid peroxidation [44]

Benzyl alcohol is contraindicated in neonates, and healthcare providers strongly advise against its use in this population

Other experimental methods, however, focus on various targets, such as the agonist of the glucagon-like peptide 1 receptor (exenatide), the urate precursor (inosine), the GBA chaperone (ambroxol), or the calcium channel antagonist (isradipine), some of which are currently being tested in Parkinson's disease clinical trials