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Antibiotic Prophylaxis Before Endoscopic Procedures Procedure Indication for antibiotics ERCP without cholangitis (complete drainage) ERCP for obstruction without cholangitis (incomplete drainage) Liver transplant EUS-FNA of solid lesion (upper or lower GI tract) EUS-FNA of mediastinal cysts EUS-FNA of pancreatic or peripancreatic cysts PEG or PEJ initial placement Cirrhosis with GI bleeding Synthetic vascular graft OR prosthetic joints Lower endoscopy in patient undergoing peritoneal dialysis No Yes