Frontotemporal dementia (FTD) is a severe neurodegenerative disease, and novel drugs that target neuroinflammation may aid in its treatment
7 Tesla (7T) proton magnetic resonance spectroscopy (MRS) studies have shown that glutamate levels were significantly lower in first episode psychosis (FEP) subjects, whereas glutamine levels were unaltered (33)
The addition of exogenous ROS results in resensitization of cells with high VRK2 expression to GSH inhibition, which is consistent with the fact that PC cells with low expression of VRK2 are susceptible to GSH inhibition attributes to its high basal ROS level, suggesting that cells in a state of oxidative stress have enhanced dependence on the GSH system
Conclusions This review highlights that creatine, traditionally used to enhance physical performance, shows promise as an adjunctive management option for depression
Likewise, The principal SLU-PP-332 paper described a synthetic pan-ERR agonist with its greatest potency at ERR and reported exercise-associated effects in cells and mice
