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Mitochondrial dysfunction, therefore, contributes to both reduced motility and compromised sperm DNA integrity ( Given the central role of oxidative stress in male infertility, this review aims to provide a detailed exploration of the molecular mechanisms by which oxidative stress induces sperm dysfunction

After washing, sections were blocked with the Avidin/Biotin Blocking Kit (Vector Laboratories, SP-2001) if GARbio/RAGbio secondary antibodies were used (for ferroportin and GPX4)

GGC also upregulated the level of the anti-inflammatory cytokine IL-10 and reduced the levels of the pro-inflammatory cytokines (TNF-, IL-6, and IL-1) and attenuated the changes in metalloproteinase activity in oligomeric A 40 -treated astrocytes

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