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The MDM2 inhibitor nutlin-3a suppresses abnormal T-cell expansion and reduces systemic inflammation in SLE models, highlighting an immunoregulatory role for MDM2 inhibition beyond oncology

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Diabetes Care 35 , 731737 (2012)

[DOI] [PMC free article] [PubMed] [Google Scholar] 50.Tavilani H, Goodarzi MT, Doosti M, et al

In contrast to the present findings in humans with compensated liver cirrhosis, some animal studies did provide evidence of oxidative stress in the small and large intestine of rats with carbon tetrachloride (CCl4)-induced liver cirrhosis, although part of them had ascites.13,2426 Published data on the occurrence of intestinal oxidative stress in cirrhotic patients are scarce