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Antioxidant defenses, including GSH synthesis and utilization, demonstrate regional heterogeneity across the brain

Data Availability All data generated or analyzed during this study are included in this published article

A small catheter goes into a vein, usually in your forearm or the back of your hand

Bicarb 3.0 wraps micro-beadlets of bicarb in a sodium alginate gel matrix that protects them through your stomach and releases in your small intestine where absorption is clean

Maximal Oxygen Consumption The maximal oxygen consumption (VO 2 max) test was performed as described previously (Hirschberg et al., 2020)